Faculty of Basic Medical Sciences

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Browsing Faculty of Basic Medical Sciences by Author "Atunnise, Adeleke"

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    Cyanogenic Glycosides Retention in Juiced and Blanched Leafy Vegetables Commonly Consumed in South-Western Nigeria
    (SCIENCEDOMAIN international, 2016-10-06) Atunnise, Adeleke
    Vegetable is one of the rich sources of phytonutrients and it is part of the dietary components of in habitants of south-western Nigeria. Despite its nutritional and health benefits, it is not without other factors that are detrimental to health such as anti-nutrinets like cyanogenic glycosides. Comparative evaluation of the effect of juicing and blanching on cyanogenic glycoside was investigated in ten (10) leafy vegetables commonly consumed in southwest Nigeria.Varying cyanogenic glycoside content was noted among the leafy vegetables. Blanching significant reduced cyanogenic glycoside in vitually all the vegetables except Talinum triangulare which retained about 70% of its cyanogenic glycosides contents after 5 minutes exposure to boiling water. Also, reduction was observed in juicing but to a lesser magnitude. Thus, blanching is more effective in reducing cyanogenic glycoside when compared with juicing; hence further treatment may be required for Talimun triangulare because of its resistance to blanching in reducing its cyanogenic glycoside.
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    Enhancement of Bioactive Compounds During Fermentation of Unripe Musa paradisiaca
    (Science Alert, 2020-12) Atunnise, Adeleke
    Background and Objective: Plantain is known as a rich source of several bioactive components yet there are several local claims on how those bioactive components could be promoted by employing fermentation. This study was set to investigate the effect of fermentation on the phytochemical constituents; exploring Fourier Transformer Infrared (FTIR) spectroscopy and Ultraviolet-visible (UV) spectroscopy for possible detection of structural modifications on phytochemicals as well as to evaluate the impact of fermentation on the antioxidants potentials on unripe plantain fruit extract. Materials and Methods: Plantain fruit was sourced at a local market in Ede, Osun state, Nigeria, peeled, washed, homogenized with distilled water; the proximate, phytochemical, FTIR, UV and antioxidants analyses were investigated. Results: Fermentation significantly increased protein content while crude and soluble fibre fraction reduced significantly. All the selected phytochemical components increased significantly except for saponin and tannin that remain unaffected. The FTIR and UV analyses showed that the fermentation process resulted in the modification of some bioactive compounds (quercetin to quercetagetin, flavones and 2"-O-Xywsylvitexin) and formation of a class of phenolics (p-coumaric acid). Conclusion: This study showed the antioxidant potential of unripe M. paradisiaca could be greatly amplified through fermentation; hence the formation of a new compound could be the key behind these potentials
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    JUICED Telfairia Occidentalis Leaf Moderates Sugar-Induced Lipids Disorders in Rats
    (Federal University Wukari Taraba State, Nigeria, 2022-05-20) Atunnise, Adeleke
    Dyslipidemia and other lipids dysregulation caused by high sucrose diet have been well documented. Modulation of lipids metabolic disorders have been approached with various therapeutics models of which plants components are reverberating. The comparative effect of the whole form, juiced, and pulp fractions of Telfairia Occidentalis leafy vegetable modified diets (TDs) on the sucrose-induced lipid dysfunction in the brain, heart and liver of the Wistar rats were investigated in this study. The Wistar rats were fed a diet of 30% energy supplied by sucrose (high sucrose diet) (SD) for twelve weeks. Three other rat groups were fed high sucrose diet modified with either the whole, juiced or pulp fractions to assess the effect of leafy vegetables as a food supplement. After twelve weeks, the selected lipids constituents were assayed, and the results were analysed statistically. This study showed that sucrose consumption within twelve weeks induced impaired lipids regulation in some selected organs by increasing (p<0.05) cholesterol in the heart and liver; triglycerides in the brain, heart and liver. Also, proportions of the organ to body weight (ORG: BDY) and lipids biomarkers were moderated by TDs in the three organs while SD decreased (p<0.05) ORG: BDY and increased (p<0.05) total lipids in the organs. Hence, the T. Occidentalis-modified diets reversed SD induced lipids toxicity across all the organs investigated. Additionally, the juiced fraction of the T. Occidentalis-modified diet showed to be more potent than other forms of T. Occidentalis-diet against sugar-induced lipids disorders.