JUICED Telfairia Occidentalis Leaf Moderates Sugar-Induced Lipids Disorders in Rats
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Date
2022-05-20
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Publisher
Federal University Wukari Taraba State, Nigeria
Abstract
Dyslipidemia and other lipids dysregulation caused by high sucrose diet have been well
documented. Modulation of lipids metabolic disorders have been approached with various therapeutics
models of which plants components are reverberating. The comparative effect of the whole form, juiced,
and pulp fractions of Telfairia Occidentalis leafy vegetable modified diets (TDs) on the sucrose-induced
lipid dysfunction in the brain, heart and liver of the Wistar rats were investigated in this study. The
Wistar rats were fed a diet of 30% energy supplied by sucrose (high sucrose diet) (SD) for twelve weeks.
Three other rat groups were fed high sucrose diet modified with either the whole, juiced or pulp fractions
to assess the effect of leafy vegetables as a food supplement. After twelve weeks, the selected lipids
constituents were assayed, and the results were analysed statistically. This study showed that sucrose
consumption within twelve weeks induced impaired lipids regulation in some selected organs by
increasing (p<0.05) cholesterol in the heart and liver; triglycerides in the brain, heart and liver. Also,
proportions of the organ to body weight (ORG: BDY) and lipids biomarkers were moderated by TDs
in the three organs while SD decreased (p<0.05) ORG: BDY and increased (p<0.05) total lipids in the
organs. Hence, the T. Occidentalis-modified diets reversed SD induced lipids toxicity across all the
organs investigated. Additionally, the juiced fraction of the T. Occidentalis-modified diet showed to be
more potent than other forms of T. Occidentalis-diet against sugar-induced lipids disorders.
Description
Keywords
Atherogenic-Index, Juiced-vegetables, Lipid-disorders, Sucrose diet, Telfairia occidentalis
Citation
Kuburat T. Odufuwa, Adeleke K. Atunnise, TiOluwani B. Salau, Muinat M. Adeyanju, Olusegun L. Adebayo, Bamidele A. Salau (2022). JUICED Telfairia Occidentalis LEAF MODERATES SUGAR-INDUCED LIPIDS DISORDERS IN RATS. FUW Trends in Science & Technology Journal 3(1) 694 - 707.