High Sucrose Diet Modulates Calcium Status in Male Albino Rats: Possible Implication on Cardiovascular Disease and Dental Caries

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dc.contributor.authorAdebayo, Olusegun
dc.date.accessioned2022-02-18T08:56:18Z
dc.date.available2022-02-18T08:56:18Z
dc.date.issued2014
dc.description.abstractEffects of various concentrations of sucrose diet were assessed on calcium status of thirty weanling male albino rats randomly divided into five equal groups as follows: G1 (baseline group); G2 (control group; rat chow only); G3, G4 and G5 (experimental groups; with energy supply from sucrose at 10, 20 and 30 percent respectively). The experimental groups were fed for twelve weeks; standard laboratory procedures were used to determine feed and nutrient intakes; feaces and urine were taken for calcium estimation, the rats were fasted overnight, anaesthetized with diethyl ether and blood was collected using cardio puncture method. Bones and teeth were removed washed, dried and ashed. Plasma was collected by centrifugation, urinary and plasma calcium was assessed by enzymatic kits while feacal, bone and teeth calcium were assessed using standard laboratory methods. Analyses revealed that inclusion of sucrose at concentration of 20 percent of energy supply significantly increased (p<0.05) plasma calcium, 59.54 percent and urinary calcium, 125.72 percent. Significant decrease (p<0.05) was observed in faecal calcium, 9.54 percent; bone calcium, 3.21 percent and teeth calcium, 15.98 percent. The study revealed that consumption of sucrose at twenty percent energy supply may reduce teeth and bone calcium which may affect their integrity; increased plasma calcium which may affect cardiovascular risk factors in albino rats. Consequently, current recommendation of WHO/FAO stating that sucrose should not supply more than ten percent of energy intake rather than upper limit of twenty five percent set by IOM of Food and Nutrition Board must be adhered to.en_US
dc.identifier.citation0en_US
dc.identifier.issn2348-1927
dc.identifier.urihttp://dspace.run.edu.ng:8080/jspui/handle/123456789/1317
dc.language.isoenen_US
dc.publisherBioscienceen_US
dc.relation.ispartofseries2(2);45-50
dc.subjectSucrose dietsen_US
dc.subjectDental carriesen_US
dc.subjectCalcium statusen_US
dc.subjectCardiovascular diseaseen_US
dc.subjectRatsen_US
dc.titleHigh Sucrose Diet Modulates Calcium Status in Male Albino Rats: Possible Implication on Cardiovascular Disease and Dental Cariesen_US
dc.typeArticleen_US
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High sucrose diet altered calcium status by increasing plasma and urinary calcium levels; decreasing feacal, bone and teeth calcium contents, which may adversely affect cardiovascular, bone and dental health.
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