Isoxazole Derivatives: The Search for Anticancer Drugs
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Date
2017
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Chemical Research Journal
Abstract
Abstract Over the last seven years, there has been a continuous interest towards structural modification of isoxazole heterocycle in order to develop anticancer agents. This quest culminated in the syntheses of a large number of compounds and their evaluation against several cancer cell lines. In this paper, emphasis is made on reporting the synthesis and anticancer studies of selected compounds that exhibited a spectacular activity against the different cancer cell lines.
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Review
Keywords
Anticancer activity, Isoxazoles, Synthesis, Hybrid molecules