Bioactive Components of Ficus exasperata, Moringa oleifera and Jatropha tanjorensis Leaf Extracts and Evaluation of their Antioxidant Properties

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dc.contributor.authorAvwioroko, Oghenetega
dc.date.accessioned2022-09-14T11:07:32Z
dc.date.available2022-09-14T11:07:32Z
dc.date.issued2019
dc.description.abstractPurpose: This study investigated the phytochemistry and in vitro free radical scavenging activities of aqueous leaf extract of Ficus exasperata (FE), Moringa oleifera (MO) and Jatropha tanjorensis (JT). Methods: Spectrophotometric evaluation was employed in the determination of the total phenols, total flavonoids, 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical inhibition, nitric oxide (NO●) radical inhibition, ferric reducing antioxidant power (FRAP) and total antioxidant capacity (TAOC). Results: Qualitative screening of bioactive compounds confirmed the presence of terpenes, flavonoids and phenols in all extracts amidst other phytochemicals. Total phenols and total flavonoids estimation were highest in Ficus exasperata (96.10 ± 2.70 mg gallic acid equivalent g-1 and 28.45 ± 1.80 mg catechin equivalent g-1, respectively). Moringa oleifera leaf extract exhibited the highest radical scavenging activity against DPPH and NO● radicals, while Jatropha tanjorensis exhibited the highest FRAP and TAOC. Nitric oxide radical inhibition by M. oleifera extract was significantly higher (p<0.05) at 7.0 mg mL-1 (64.7 ± 0.32%). The 50% inhibitory concentration (IC50) values of the plant leaves for FRAP and TAOC were in the order JT < MO < FE, whereas for DPPH and NO● scavenging activities the IC50 values were in the order MO < JT < FE. Conclusions: The findings of this study clearly showed that the antioxidant properties of M. oleifera and J. tanjorensis leaves were higher than those of F. exasperata. The knowledge of the different bioactive components and antioxidant prowess of these medicinal plants could be used as a guide in making the choice of medicinal plant to use for treatment or prophylaxis against cellular aberrations in which oxidative stress is implicated.en_US
dc.identifier.citationAnigboro AA, Avwioroko OJ, Ohwokevwo OA, Pessu B (2019) Bioactive components of Ficus exasperata, Moringa oleifera and Jatropha tanjorensis leaf extracts and evaluation of their antioxidant properties. Eurasia J Biosci 13: 1763-1769.en_US
dc.identifier.urihttp://dspace.run.edu.ng:8080/jspui/handle/123456789/3614
dc.language.isoenen_US
dc.publisherEurAsian Journal of BioSciencesen_US
dc.relation.ispartofseries13,;1763-1769
dc.subjectAntioxidanten_US
dc.subjectFicus exasperataen_US
dc.subjectFree radicalsen_US
dc.subjectJatropha tanjorensisen_US
dc.subjectMoringa oleiferaen_US
dc.titleBioactive Components of Ficus exasperata, Moringa oleifera and Jatropha tanjorensis Leaf Extracts and Evaluation of their Antioxidant Propertiesen_US
dc.typeArticleen_US
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