Obesity and the Maternal Lipid WƌŽĮůĞ͗ Role of Diet in ƉŝŐĞŶĞƟĐ Transfer on the KīƐƉƌŝŶŐ
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Date
2021-02-15
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iMedPub Journals
Abstract
Aim: /nvĞƐƟŐĂƚĞ the ŝmƉůŝcĂƟŽnƐ of High Fat Diet (HFD)
induced obesity on the lipid ƉrŽĮůĞ in parent rats and their
ŽīƐƉrŝnŐ͘
Methodology: Twenty adult female rats were grouped into
A and B which received NRC and HFD rĞƐƉĞcƟvĞůy for 16
obese. Adult male Wistar rats fed with NRC were introduced
to each group to ensure mĂƟnŐ and pregnancy ĂŌĞr
feeding. The ŽīƐƉrŝnŐ produced by the rats in each group
were divided into two groups of 20 rats each. They were fed
with NRC for 12 months. The plasma obtained from the
parent and ŽīƐƉrŝnŐ were analysed for lipid ƉrŽĮůĞ test.
Results: The parent rats fed with HFD had higher cholesterol
triglyceride and HDL compared with the rats fed with NRC.
At 4 and 12 months the ŽīƐƉrŝnŐ of HFD fed rats had lower
triglyceride and LDL compared with ŽīƐƉrŝnŐ of NRC fed
rats. The ŽīƐƉrŝnŐ of HFD fed rats had higher HDL compared
with the ŽīƐƉrŝnŐ of NRC fed rats at 8 months.
Conclusion: KīƐƉrŝnŐ of obese HFD fed rats placed on NRC
did not manifest the consequence of maternal obesity as
depicted by their lipid ƉrŽĮůĞ͘
Description
Keywords
Obesity; High fat diet; Normal rat chow; Triglyceride