Depression in Sub-Saharan Africa
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Date
2022-06
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Elsevier Ltd
Abstract
Mood disorders can be considered among the most common and debilitating mental disorders. Major depression, as an example of mood disorders, is known to severely reduce the quality of life as well as psychosocial functioning of those affected. Its impact on the burden of disease worldwide has been enormous, with the World Health Organization projecting depression to be the leading cause of mental illness by 2030. Despite several studies on the subject, little has been done to contextualize the condition in Africa, coupled with the fact that there is still much to be understood on the subject. This review attempts to she d more light on the prevalence of depression in Sub-Saharan Africa (SSA), its pathophysiology, risk factors, diagnosis and the experimental models available to study depression within the sub-region. It also evaluates the contribution of the sub-region to the global research output of depression as well as bottlenecks associated with full exploitation of the sub region’s resources to manage the disorder.
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Keywords
Major depressive disorder, Sub-Saharan Africa, Antidepressants, Medicinal plants
Citation
Ismail Temitayo Gbadamosi, Isaac Tabiri Henneh, Oritoke Modupe Aluko, Emmanuel Olusola Yawson, Aliance Romain Fokoua, Awo Koomson, Joseph Torbi, Samson Ehindero Olorunnado, Folashade Susan Lewu, Yusuf Yusha'u, Salmat Temilola Keji-Taofik, Robert Peter Biney, Thomas Amatey Tagoe, Depression in Sub-Saharan Africa, IBRO Neuroscience Reports, Volume 12, 2022, Pages 309-322, ISSN 2667-2421, https://doi.org/10.1016/j.ibneur.2022.03.005. (https://www.sciencedirect.com/science/article/pii/S2667242122000173)