Oxidative Damage on the Testes of Adult Rats by sodium metabisulfite

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dc.contributor.authorAdebayo, Olusegun
dc.date.accessioned2022-02-08T10:52:45Z
dc.date.available2022-02-08T10:52:45Z
dc.date.issued2012
dc.description.abstractThe effect of sodium metabisulfite (MBS, Na2S2O5) on the level of malondialdehyde (MDA), testes weight and the activities of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT) as well as the level of glutathione (GSH) were investigated in the testes of Wistar albino rats. The study was performed to elucidate the effect of MBS (520 mg/kg/day) ingestion on lipid peroxidation and the antioxidant enzymes activities. The results showed that MDA level as well as the activity of SOD was significantly increased in MBS-treated rats whereas the weight of the testes as well as the level of GSH was not significantly affected. However, there was significant reduction in the activity of CAT in the MBS-treated rats compared to the control. The presented data showed that ingestion of MBS has adverse effect on testes as it induced oxidative damage, reflected by increase lipid peroxidation and impairment in the activities of antioxidant enzymes.en_US
dc.identifier.citation16en_US
dc.identifier.issn1991-8631
dc.identifier.urihttp://dspace.run.edu.ng:8080/jspui/handle/123456789/1084
dc.language.isoenen_US
dc.publisherInternational Formulae Groupen_US
dc.relation.ispartofseries6(2);738-744
dc.subjectSodium metabisulfiteen_US
dc.subjectTestesen_US
dc.subjectSuperoxide dismutaseen_US
dc.subjectLipid peroxidationen_US
dc.subjectGlutathioneen_US
dc.subjectCatalaseen_US
dc.titleOxidative Damage on the Testes of Adult Rats by sodium metabisulfiteen_US
dc.typeArticleen_US
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Consumption of sodium metabisulfite has adverse effect on testes as it induced oxidative damage by increasing lipid peroxidation and causes reduction in the activities of antioxidant enzymes.
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