Chemical constituents, toxicity and antimicrobial activities of the essential oil from the leaves of tectona grandis
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Date
2013-07-28
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Elixir
Abstract
The leaves of Tectona grandis (Verbanaceae) was subjected to hydrodistillation in order to obtain the essential oil from the plant. The pale yellow essential oil gave a percentage yield of 0.184%. Relative percentages of individual component were analyzed by GC/GC-MS. A total of fifty-four (54) constituents were identified representing 86.5% of the total essential oil fraction. Oxygenated monoterpenes, sesquiterpene hydrocarbons, oxygenated sesquiterpenes, apocarotenoids, phenylpropanoids and non-terpene derivatives were the various classes of compounds identified. The LC50 value from the brine shrimp toxicity assay was 183.29μg/ml. The oil extract was also subjected to antibacterial assay and it showed significant activities against all the clinical test organisms used except Pseudomonas aeruginosa.
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Keywords
Tectona grandis, Verbenaceae, Hydrodistillation, Apocarotenoids, Pseudomonas aeruginosa, Artemia salina