Phytochemical Screening and Antibacterial Activity of Two Plant Extracts against Multidrug-Resistant Stenotrophomonas maltophilia of Clinical Origin.
| dc.contributor.author | Sossou, Ibukun T. | |
| dc.date.accessioned | 2025-05-22T08:17:12Z | |
| dc.date.available | 2025-05-22T08:17:12Z | |
| dc.date.issued | 2023 | |
| dc.description.abstract | New antibacterial agents are pressingly in need to combat the outgrowing incidence of bacterial resistance, which has been number one significant public health threat. The antibacterial activity and phytochemical components of Cannabis sativa and Garcinia kola against Stenotrophomonas maltophilia from diabetic patients with wound infection were investigated. Pure and type isolates of S. maltophilia (ATCC 17666) were obtained from Ogun and Lagos State hospitals, while the plants used were purchased from Ago-Iwoye market, Ogun State. Disk and agar diffusion methods were used to evaluate the antibacterial profile, and the effect of the extracts on the studied isolates, respectively. The isolates of S. maltophilia were resistant to all the antibiotics tested. The effect of the two extracts on the two S. maltophilia varied based on the plant solvent, concentration, and organisms. Ethanol extracts of G. kola and C. sativa on pure/type S. maltophilia had the highest diameter zones of inhibition of 24 mm/27 mm and 19 mm/22 mm at 150 mg/ml, respectively. The type isolate had the highest diameter zones of inhibition in all concentrations of the solvent extracts except for the aqueous. Minimum inhibitory and bactericidal concentration for both plants were 75 mg/ml (type isolate), 150 mg/ml (pure isolate), and 75 mg/ml for C. Sativa alone. Some phytochemicals such as alkaloids, flavonoids, tannins, saponins were observed in the plant extracts.In conclusion, the tested plants possess antibacterial activity, hence, could be used as substitutes in the treatment and management of S. maltophilia pathogens in diabetics with wound infection, and also, in the formulation of pharmaceuticals. | |
| dc.identifier.other | 6619 - 6631 | |
| dc.identifier.uri | https://repository.run.edu.ng/handle/123456789/4603 | |
| dc.language.iso | en | |
| dc.publisher | Nigerian Journal of Microbiology | |
| dc.relation.ispartofseries | Vol. 37; No. 2 | |
| dc.title | Phytochemical Screening and Antibacterial Activity of Two Plant Extracts against Multidrug-Resistant Stenotrophomonas maltophilia of Clinical Origin. | |
| dc.type | Article |