Antioxidant Defense of zinc acetate Supplementation on the Brain of Protein–undernourished Rats

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dc.contributor.authorAdebayo, Olusegun
dc.date.accessioned2022-02-08T11:04:51Z
dc.date.available2022-02-08T11:04:51Z
dc.date.issued2009
dc.description.abstractThe effect of zinc on brain weight, glutathione (GSH) level, catalase activity and lipid peroxidation in the brain of protein-undernourished (PU) rats was investigated following the ad libitum ingestion of zinc acetate (30 mg/L) in drinking water for two weeks. Results show that protein-undernutrition induced significant reductions (P<0.01) in brain weight and catalase activity while it induced a significant increase (P<0.05) in lipid peroxidation when compared with well-nourished rats; but no significant effect was observed on GSH level. The ingestion of zinc acetate, however, by PU rats had no significant effect on brain weight but induced significant increase in catalase activity. There were also reductions (P<0.05) in lipid peroxidation and GSH level. These results show that zinc acts as an antioxidant but is ineffective in ameliorating some of the biochemical changes associated with protein-undernutrition-induced brain damage particularly reduction in brain weight.en_US
dc.identifier.citation6en_US
dc.identifier.issn1991-8631
dc.identifier.urihttp://dspace.run.edu.ng:8080/jspui/handle/123456789/1093
dc.language.isoenen_US
dc.publisherInternational Formulae Groupen_US
dc.relation.ispartofseries3(1);152-155
dc.subjectProtein-undernutritionen_US
dc.subjectOxidative stressen_US
dc.subjectBrain weighten_US
dc.subjectLipid peroxidationen_US
dc.subjectGlutathioneen_US
dc.subjectCatalaseen_US
dc.titleAntioxidant Defense of zinc acetate Supplementation on the Brain of Protein–undernourished Ratsen_US
dc.typeArticleen_US
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