Faculty of Basic Medical Sciences

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Possible Implication of Long Term Sucrose Diet on Integumentary Tissues’ Minerals of Male Albino Rats
(Trends in Medical Research, 2020) Avwioroko, Oghenetega
Background and Objective: The role of sucrose in the biochemical derangement in many tissues/organs has been established. However, there is a dearth of information about its effect on mineral status in integumentary tissues such as hair, nail, and skin in male albino rats. This study investigated minerals response in some selected integumentary tissues and possible implications on their integrity and performance in rats fed sucrose diet. Materials and Methods: Eighteen male albino rats were grouped into three with varying concentrations of sucrose supplying energy at 0% (G1), 10% (G2) and 20% (G3), respectively. Animals were fed for six months and the hair, nail and skin were harvested for calcium, phosphorus and magnesium analyses. Results: Substantial increase was observed in phosphorus and magnesium, while a decrease was noted in calcium levels in tissues as sucrose consumption increased . Conclusion: We opined that the alterations in mineral levels occasioned by sucrose concentration in the diet might adversely affect the integrity and function of integumentary tissues