Synthesis, Antimalarial Activity, and Docking Studies of Monocarbonyl Analogues of Curcumin

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dc.contributor.authorAjibade, Sunday
dc.date.accessioned2022-03-01T12:39:12Z
dc.date.available2022-03-01T12:39:12Z
dc.date.issued2018
dc.description.abstractThe synthesis of five monocarbonyl analogues of curcumin is described. In vitro anti-malarial assay of the compounds was carried out and the effect of the substituents on the aryl ring has been described. The results show that all the five compounds exhibited some reasonable activity against the chloroquine-resistant plasmodium parasite. Molecular docking studies further confirmed the observed biological activity of the compounds.en_US
dc.identifier.urihttp://dspace.run.edu.ng:8080/jspui/handle/123456789/1563
dc.language.isoenen_US
dc.publisherOvidius University Annals of Chemistry; 29, 2, 92-96. DOI: 10.2478/auoc-2018-0013en_US
dc.subjectCurcuminen_US
dc.subjectMonocarbonyl analoguesen_US
dc.subjectAntimalarial activityen_US
dc.subjectDocking studiesen_US
dc.titleSynthesis, Antimalarial Activity, and Docking Studies of Monocarbonyl Analogues of Curcuminen_US
dc.typeArticleen_US
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