Essential Oils: Therapeutic Effects as Anthelmintics

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dc.contributor.authorAkande, Akinsola
dc.date.accessioned2022-03-18T14:44:32Z
dc.date.available2022-03-18T14:44:32Z
dc.date.issued2020
dc.description.abstractThe rate at which ignorance of hygiene and sanitary practices is being neglected in the suburban and rural areas of developing regions of the world never seem to reduce. Lack of adequate sanitation and health facilities together with deficiency in educating these rural dwellers on how to maintain proper hygiene has made the prevalence and impact of helminthiasis on public health and animal production a great socio-economic problem. Often associated with these problems are conditions such as anaemia, malnutrition, vitamin deficiencies, poor cognitive ability, less intellectual and mental development which are prominent in underage children and pregnant women. Animal health care and husbandry has also been hit as a result of this inadequate hygiene and sanitary practices which thus pose great challenge in food production. Most of the domestic animals serve as primary host to infectious helminths (worms) from which they are transmitted into humans. However, many naturally occurring secondary metabolites (phytochemicals) of plants such as terpenoids from essential oils, alkaloids, flavonoids, glycosides and tannins have been explored as leads to develop medicines for a disease-free and healthy society. Plants essential oils are ingredients present in formulations used ethno-medicinally, pharmaceutically, in food and cosmetic industries due to their potential bioactive and therapeutic activities against a wide spectrum of pathogenic organisms. Results from many reported researches as well as from our research findings, using the essential oils of plants from the Fabaceae species, showed the efficacy of some of these plant constituents as anthelminthics against various test organisms. The essential oils explored from plants of choice premised on their ethnobotanical survey in the treatment of one or more gastrointestinal troubles (GIT). The different essential oils studied demonstrated varying inhibitory activities (in vitro and in vivo) against different classes of helminth parasites (nematodes, cestodes, trematodes) and annelids which could be a lead to developing potent anthelmintics. As a result of these findings, the discovery of natural plant constituents should be kept on-going.en_US
dc.identifier.isbn978-1-53617-986-6
dc.identifier.urihttp://dspace.run.edu.ng:8080/jspui/handle/123456789/2077
dc.language.isoenen_US
dc.publisherNova Scienceen_US
dc.subjectPhytochemicalen_US
dc.subjectHelminthiasisen_US
dc.subjectTerpenoidsen_US
dc.subjectHygieneen_US
dc.titleEssential Oils: Therapeutic Effects as Anthelminticsen_US
dc.typeBook chapteren_US
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