Comparative Study of the Antibacterial and Cytotoxicity of the Essential Oils from the Leaves, Stem Bark and Roots of Blighia unijugata Baker (Sapindaceae)
No Thumbnail Available
Date
2009-07-01
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Global Science Books
Abstract
The antimicrobial activity of the essential oils (EOs) from Blighia unijugata Baker (Sapindaceae) was studied. EO was extracted from the
leaves (BUL), stem bark (BUB) and roots (BUR) by hydrodistillation. These were all colorless and soluble in water except for BUB. The
EOs were active against Proteus mirabilis, Salmonella typhi, Escherichia coli, Bacillus subtilis and Pseudomonas mallei. BUB EO had
the highest inhibitory zone (40 mm) against E. coli. BUB was also active against all the tested organisms except for P. fluorescens. All the
EOs exhibited significant inhibitory activity against the pathogenic microorganisms. They all showed potent cytotoxicity with an LC50 of
85.20 μg/ml (BUL), 70.50 μg/ml (BUR) and 155.10 μg/ml (BUB), which suggests an ethnomedicinal application of these EOs.